a Vitamin A related compound that inhibits sebaceous gland function and reformation of the outermost layer of skin. It is used in the treatment of severe acne unresponsive to antibiotics. These glands furnish the cells that repopulate the skin surface after the surface has been denuded. If the depth of denuding is deep enough to affect the depths of these glands the risk of scarring dramatically increases. The quickest healing with least scar formation occurs in areas of the skin surface that have the highest concentration of sebaceous glands i.e. the face. Major cosmetic procedures to the skin surface should be undertaken 12 to 18 months after the last dose of accutane to allow sufficient time for sebaceous gland recovery & avoid bad scarring. Accutane slows the skin surface healing process.