a soft tissue filler that consists of microscopic Plexiglass plastic beads suspended in bovine collagen. When the bovine collagen reabsorbs, the tiny spheres trigger the body to produce its own collagen to envelop them-making it a permanent tissue filler. It has been available in Europe since the late 1980’s but as of mid 2001 had not been approved for use in the US by the FDA. It can yield a lumpy appearance which is permanent. It was bought by another company reworked with small more uniform shaped spheres and is not marketed as Bellafill.